Post Traumatic Brain Injury Hormonal Deficiency Syndrome

Traumatic brain injury (TBI), typically resulting from vehicle accidents or acts of violence, is a major public health concern. Survivors often face lifelong impairments affecting functional status, memory, cognition, language, and mood, as well as physical functioning and metabolism. Within the past three years, a clear cause and effect has been established – post TBI hormonal deficiency syndrome. Prior to this new knowledge patients have been treated with symptomatic protocols that simply did not work. There is an increasing amount of evidence to suggest that post TBI hormonal deficiency syndrome affects many people who have sustained TBI and mild TBI, and research is now beginning to show that replacement of deficient hormones can lead to significant improvements. This paper will consider the incidence, clinical course, diagnosis, and treatment of post TBI hormonal deficiency syndrome.